* This analysis evaluated direct benefits and harms, per million second doses of mRNA COVID-19 vaccine given in each age group, over 120 days. Most people recover fully with rest and a few days of supportive treatment while being monitored in a hospital. July 5, 2022, U.S. Department of Health and Human Services, Benefits of COVID-19 vaccines outweigh a very small risk of heart complications, You can learn more about myocarditis symptoms, diagnosis, and treatment from the NHLBI, Countermeasures Injury Compensation Program, Researching COVID to Enhance Recovery (RECOVER), CONNECTS-Collaborative Cohort of Cohorts for COVID-19 Research (CONNECTS-C4R), https://covid.cdc.gov/covid-data-tracker/#vaccinations_vacc-total-admin-rate-total, https://doi.org/10.1161/CIR.0000000000001001, https://doi.org/10.1038/s41591-021-01630-0, https://doi.org/10.1016/j.hrtlng.2020.08.013, https://doi.org/10.1007/s12471-022-01677-9, https://doi.org/10.1016/j.vaccine.2020.12.046, https://doi.org/10.1016/j.ijcard.2022.01.037, https://doi.org/10.1007/s00392-022-02007-0, https://doi.org/10.1016/j.mayocpiqo.2021.12.006, https://doi.org/10.1177/01410768211052589, https://doi.org/10.1101/2021.10.05.21264581. The walls of the heart become inflamed, which weakens the hearts pumping action and can cause irregular heart rhythms, heart failure, and other complications. Centers for Disease Control and Prevention. The F.D.A. Among men ages 18 to 29 who received the Moderna vaccine, the rate was 22.9 per 100,000 doses. Members of the Advisory Committee on Immunization Practices COVID-19 Vaccines Safety Technical Work Group: Robert Hopkins, National Vaccine Advisory Committee; Kathryn Edwards, Vanderbilt University School of Medicine; Lisa Jackson, Kaiser Permanente Washington Health Research Institute; Jennifer Nelson: Kaiser Permanente Washington Health Research Institute; Laura Riley, American College of Obstetricians and Gynecologists; Patricia Whitley-Williams, National Medical Association; Tatiana Beresnev, National Institutes of Health; Karen Farizo, Food and Drug Administration; Hui Lee Wong, Food and Drug Administration; Judith Steinberg, U.S. Department of Health and Human Services; Matthew Clark, Indian Health Service; Mary Rubin, Health Resources & Services Administration; Fran Cunningham, Veterans Administration; Limone Collins, Department of Defense. The y-axis range differs between panels A and B. COVID-19 vaccines lower the risk of life-threatening heart problems and other serious health issues. Chou, O., Zhou, J., Lee, T., Kot, T., Lee, S., Wai, A., Wong, W. T., Zhang, Q., Cheng, S. H., Liu, T., Vassiliou, V. S., Cheung, B., & Tse, G. (2022). But as report after report showed such. Payne AB, Gilani Z, Godfred-Cato S, et al. The FDA - which generally follows the recommendations of its advisers but is not obligated to do so - is likely to authorize the Moderna vaccine for ages 6-17 soon. 2023 Feb 11;15(2):508. doi: 10.3390/v15020508. Autopsy cases may be classified as confirmed clinical myocarditis on the basis of meeting histopathologic criteria if no other identifiable cause. To meet the ECG or rhythm monitoring criterion, a probable case must include at least one of 1) ST-segment or T-wave abnormalities; 2) Paroxysmal or sustained atrial, supraventricular, or ventricular arrhythmias; or 3) AV nodal conduction delays or intraventricular conduction defects. Using either the original or the revised Lake Louise criteria. CDC and its partners are actively monitoring reports of myocarditis and pericarditis after COVID-19 vaccination. As of June 11, 2021, approximately 296 million doses of mRNA COVID-19 vaccines had been administered in the United States, with 52 million administered to persons aged 1229 years; of these, 30 million were first and 22 million were second doses. According to the US Centers for Disease Control and Prevention, myocarditis/pericarditis rates are 12.6 cases per million doses of second-dose mRNA vaccine among individuals 12 to 39 years of age. Hromi-Jahjefendi A, Barh D, Uversky V, Aljabali AA, Tambuwala MM, Alzahrani KJ, Alzahrani FM, Alshammeri S, Lundstrom K. Vaccines (Basel). Hamedi KR, Loftus G, Traylor L, Goodwin R, Arce S. Vaccines (Basel). Buonsenso D, Munblit D, De Rose C, et al. We dont know exactly how often this happens, but one study estimated that myocarditis affects about 40 people out of every 1,000,000 people who test positive for COVID-19.3 However, myocarditis is much more common in patients hospitalized for COVID-19 (226 per 100,000). Would you like email updates of new search results? * These authors contributed equally to this work. When reported, the cases have especially been in adolescents and young adult males within several days after mRNA COVID-19 vaccination (Pfizer-BioNTech or Moderna). All HTML versions of MMWR articles are generated from final proofs through an automated process. Reports of myocarditis and pericarditis after vaccination are rare. Incidence of multisystem inflammatory syndrome in children among US persons infected with SARS-CoV-2. The findings from the VaST and the ACIP COVID-19 Vaccines Work Group assessments, including a summary of the data reviewed, were presented to ACIP during its meeting on June 23, 2021. Heart inflammation, or myocarditis, has been reported as a very rare side effect of COVID-19 vaccines. After reports of myocarditis, the work group met twice to review clinical trial and postauthorization safety data for myocarditis after receipt of mRNA COVID-19 vaccines. Association Between Myocarditis and Mortality in COVID-19 Patients in a Large Registry. Myocarditis and Pericarditis After mRNA COVID-19 Vaccination, Centers for Disease Control and Prevention. Currently, about 1,000 cases of myocarditis and pericarditis have been reported after vaccination against COVID-19 with one of the mRNA vaccines, Pfizer/BioNTech or Moderna. Reported cases of the rare heart . Though both complications were rare, data from Ontario show higher rates of myocarditis and pericarditis with the Moderna COVID-19 vaccine than with the Pfizer-BioNTech vaccine, but the rates were lower for both vaccines if the spacing between receiving two doses was extended, according to a study late last week in JAMA Network Open.. Myocarditis is an inflammation of the heart muscle, and . The benefit-risk analysis can be updated as needed to reflect changes in the COVID-19 pandemic and additional information on the risk for and outcomes of myocarditis after COVID-19 vaccination. Incidence Rates and Rate Ratios of Myocarditis in Vaccinated Individuals Compared With Control Groups. The analysis assumed 95% vaccine effectiveness of 2 doses of a mRNA COVID-19 vaccine in preventing COVID-19 cases and hospitalization and assessed outcomes for a 120-day period. Design, setting, and participants: Reporting rates of myocarditis > background rates for males (12-49 years, depending upon dose and manufacturer) and females (after dose 2, 12-29 . Annie, F. H., Alkhaimy, H., Nanjundappa, A., & Elashery, A. We spoke with Fleg about the risk of myocarditis linked with COVID-19 illness and with vaccines. Preliminary evidence on long COVID in children. JAMA Netw Open 2021;4:e2116420. Myocarditis reporting rates were 40.6 cases per million second doses of mRNA COVID-19 vaccines administered to males aged 1229 years and 2.4 per million second doses administered to males aged 30 years; reporting rates among females in these age groups were 4.2 and 1.0 per million second doses, respectively. Pediatrics 2011;127(Suppl 1):S4553. Exposures were first and second dose of Pfizer, AstraZeneca, Moderna, and Janssen COVID-19 vaccines. Myocarditis typically causes shortness of breath and chest pain. Researchers are still investigating what triggers myocarditis after Covid vaccination. The ACIP COVID-19 Vaccines Work Group, comprising experts in infectious diseases, vaccinology, vaccine safety, public health, and ethics, has held weekly meetings since April 2020 to review COVID-19 surveillance data, evidence for vaccine efficacy and safety, and implementation considerations for COVID-19 vaccination programs. Lancet. Viral infections, including COVID-19, are most often the cause,2 but other diseases, as well as some drugs and toxins, can also cause myocarditis. Online ahead of print. "In general, the rate of myocarditis or myopericarditis was about threefold to fourfold higher for mRNA-1273 (Moderna) vaccination than that for BNT162b2 (Pfizer-BioNTech) vaccination," the study said. OR, infants and children aged <12 years might instead have 2 of the following symptoms: troponin level above upper limit of normal (any type of troponin), Histopathologic confirmation of myocarditis, abnormal electrocardiogram (ECG or EKG) or rhythm monitoring findings consistent with myocarditis, abnormal cardiac function or wall motion abnormalities on echocardiogram, cMRI findings consistent with myocarditis, No other identifiable cause of the symptoms and findings. doi: 10.1001/jamanetworkopen.2022.18505. Some people may have minimal or no symptoms. Although numbers were too small to show rates in all subgroups by age, VSD data indicated increased risk of myocarditis in the 7 days after receipt of dose 1 or dose 2 of an mRNA COVID-19 vaccine compared with the risk 2242 days after the second dose, particularly among younger males after dose 2 (5). Posts making claims regarding the mortality rate of children diagnosed with COVID-19-linked myocarditis are viewable here, here. The Pfizer and Moderna mRNA vaccines are available in the U.S. JAMA Netw Open. Data were used for the most recent week not subject to reporting delays prior to the ACIP meeting. Severe myocarditis can cause long-lasting heart damage or even death. Among teenaged boys the group with the highest risk of myocarditis after COVID-19 vaccination the risk is between 2 and 5 times higher after SARS-CoV-2 infection than after vaccination.10, A study of children ages 12 to 17 in England estimated that COVID-19 vaccination prevented 4,500 hospitalizations, 300 ICU hospital stays, and 36 deaths during the summer of 2021 when infection rates were high.11, Children with myocarditis linked with vaccination are less likely to be hospitalized, admitted to the ICU, or need ventilator support, compared with children who had myocarditis after a COVID-19 diagnosis. mRNA Vaccine Technology: A Promising Idea for Fighting HIV, Testing of mRNA HIV vaccines in humans is underway. 2022 May 24;327(20):2019-2020. doi: 10.1001/jama.2022.5131. CDC has provided guidance regarding evaluation and management of myocarditis after mRNA COVID-19 vaccine (https://www.cdc.gov/vaccines/covid-19/clinical-considerations/myocarditis.html), as well as considerations for a second vaccine dose in persons who develop myocarditis after a first dose (https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html). 5 Vaccine-linked myocarditis is less likely to cause lingering heart problems than myocarditis due to COVID-19 illness. The scientists are monitoring the health of a diverse group of people to learn about the long-term effects of COVID, including heart problems. This conversion might result in character translation or format errors in the HTML version. Reporting rates (per 1 million doses administered) of myocarditis among females after Moderna COVID-19 vaccination, days 0-7 after vaccination (through Jan 13, 2022 6 Moderna (Females) Ages (years) Dose 1 Dose 2 18-24 0.5 5.5 25-29 0.3 5.8 30-39 0.6 0.6 40-49 0.8 1.6 50-64 0.8 0.4 65+ 0.1 0.5 85,729,766 Based on ACIPs conclusion regarding the benefit-risk assessment on June 23, 2021, COVID-19 vaccination continues to be recommended for all persons aged 12 years under the FDAs EUA. Mary Chamberland, Thomas Clark, Amanda Cohn, Frank DeStefano, Ruth Gallego, Alice Guh, Theresa Harrington, Fiona P. Havers, Lauri Hicks, Amelia Jazwa, Tara Johnson, Brian Kit, Paige Marquez, Sarah Mbaeyi, Elaine Miller, Hannah Rosenblum, Monica Parise, Kadam Patel, Pragati Prasad, David Shay, Jamila Shields, Christopher A. Taylor, Joshua Wong, CDC COVID-19 Response Team; Clinical Immunization Safety Assessment (CISA) Project; Vaccine Safety Datalink; Center for Biologics Evaluation and Research, Food and Drug Administration; Voting members of the Advisory Committee on Immunization Practices: Kevin A. Ault, University of Kansas Medical Center; Lynn Bahta, Minnesota Department of Health; Henry Bernstein, Zucker School of Medicine at Hofstra/Northwell Cohen Childrens Medical Center; Beth Bell, University of Washington, Seattle, Washington; Wilbur Chen, University of Maryland School of Medicine; Sharon E. Frey, Saint Louis University Medical School; Camille Kotton, Harvard Medical School; Sarah Long, Drexel University College of Medicine; Katherine A. Poehling, Wake Forest School of Medicine; Pablo J. Snchez, The Research Institute at Nationwide Childrens Hospital. Observed cases of myocarditis reported to VAERS after Moderna dose 2, 7-day risk period (N=216)* Age group, years Females Males Cases of myopericarditis, expected Cases of . The Researching COVID to Enhance Recovery (RECOVER) Initiative is taking place at 80 centers across the country. FDA requires that vaccine providers report to VAERS vaccination administration errors, serious adverse events, cases of multisystem inflammatory syndrome, and cases of COVID-19 that result in hospitalization or death after administration of a COVID-19 vaccine under an EUA. Members of the Advisory Committee on Immunization Practices COVID-19 Vaccines Work Group: Edward Belongia, Center for Clinical Epidemiology & Population Health, Marshfield Clinic Research Institute; Dayna Bowen Matthew, George Washington University Law School; Oliver Brooks, National Medical Association; Jillian Doss-Walker, Indian Health Service; Marci Drees, Society for Healthcare Epidemiology of America; Jeffrey Duchin, Infectious Diseases Society of America; Kathy Kinlaw, Center for Ethics, Emory University; Doran Fink, Food and Drug Administration; Sandra Fryhofer, American Medical Association; Jason M. Goldman, American College of Physicians; Michael Hogue, American Pharmacists Association; Denise Jamieson, American College of Obstetricians and Gynecologists; Jeffery Kelman, Centers for Medicare & Medicaid Services; David Kim, U.S. Department of Health and Human Services; Susan Lett, Council of State and Territorial Epidemiologists; Kendra McMillan, American Nurses Association; Kathleen Neuzil, Center for Vaccine Development and Global Health, University of Maryland School of Medicine; Sean OLeary, American Academy of Pediatrics; Christine Oshansky, Biomedical Advanced Research and Development Authority; Stanley Perlman, Department of Microbiology and Immunology, University of Iowa; Marcus Plescia, Association of State and Territorial Health Officials; Chris Roberts, National Institutes of Health; William Schaffner, National Foundation for Infectious Diseases; Kenneth Schmader, American Geriatrics Society; Bryan Schumacher, Department of Defense; Rob Schechter, Association of Immunization Managers; Jonathan Temte, American Academy of Family Physicians; Peter Szilagyi, University of California, Los Angeles; Matthew Tunis, National Advisory Committee on Immunization Secretariat, Public Health Agency of Canada; Thomas Weiser, Indian Health Service; Matt Zahn, National Association of County and City Health Officials; Rachel Zhang, Food and Drug Administration. "In general, the rate of myocarditis or myopericarditis was about threefold to fourfold higher for mRNA-1273 (Moderna) vaccination than that for BNT162b2 (Pfizer-BioNTech) vaccination," the. Myocarditis Cases After mRNA-Based COVID-19 Vaccination in the US. Even though the studies were among the largest vaccine trials in history, they were not large enough to detect very rare complications like myocarditis that occur only a few times per million vaccinations. Men under 40 who received a second dose of the Moderna vaccine had a higher risk of myocarditis following vaccination. On July 6, 2021, this report was posted online as an MMWR Early Release. Information about CDCs ongoing study of myocarditis after COVID-19 vaccination can be found here: Investigating Long-Term Effects of Myocarditis | CDC. ** The ACIP COVID-19 Vaccines Safety Technical (VaST) Work Group, comprising independent vaccine safety expert consultants, had also reviewed safety data on myocarditis after receipt of mRNA COVID-19 vaccines at its weekly meetings. The risks and outcomes of myocarditis after COVID-19 vaccination are unclear. official website and that any information you provide is encrypted The rates of myocarditis cases were highest after the second vaccination dose in adolescent males aged 12 to 15 years (70.7 per million doses of the BNT162b2 vaccine), in adolescent males aged 16 to 17 years (105.9 per million doses of the BNT162b2 vaccine), and in young men aged 18 to 24 years (52.4 and 56.3 per million doses of the BNT162b2 . This risk should be considered in the context of the benefits of COVID-19 vaccination. The most common treatment was nonsteroidal anti-inflammatory drugs (589/676; 87%). Information regarding the risk for myocarditis with mRNA COVID-19 vaccines should be disseminated to providers to share with vaccine recipients. The researchers noted 9.7 myocarditis cases per 100,000 person-years for unvaccinated males and 4.3 per 100,000 for females. Canadian public health authorities also found that the rate of myocarditis was higher for both Moderna. Information on how to submit a report to VAERS is available at https://vaers.hhs.gov/index.htmlexternal icon or 1-800-822-7967. Myocarditis rates from Vaccine Safety Datalink (VSD), based on electronic health records, were also evaluated. The data that the agencies are reviewing were provided by the Canadian government. Myocarditis reporting rates were 40.6 cases per million second doses of mRNA COVID-19 vaccines administered to males aged 1229 years and 2.4 per million second doses administered to males aged 30 years; reporting rates among females in these age groups were 4.2 and 1.0 per million second doses, respectively. An official website of the United States government. Exposures: Both Pfizer-BioNTech and Moderna vaccines are mRNA vaccines encoding the stabilized prefusion spike glycoprotein of SARS-CoV-2, the virus that causes COVID-19. https://www.cdc.gov/vaccines/covid-19/info-by-product/janssen/risk-benefit-analysis.html. : Myocarditis is an inflammation of the heart muscle. of pages found at these sites. When reported, the cases have especially been in adolescents and young adult males within several days after mRNA COVID-19 vaccination (Pfizer-BioNTech or Moderna). Vaccination with mRNA-1273 (Moderna) was associated with a significantly increased rate of myocarditis or myopericarditis, especially among individuals aged 12-39 years (adjusted hazard ratio 5.24 (95% confidence interval 2.47 to 11.12); absolute rate 5.7 (3.3 to 9.3) per 100 000 individuals aged 12-39 years within 28 days of vaccination) The work group also reviewed a benefit-risk assessment of myocarditis events after receipt of mRNA COVID-19 vaccines, considering recent epidemiology of COVID-19 and sequelae of COVID-19, including myocarditis and multisystem inflammatory syndrome in children (MIS-C). Myocarditis after RNA-based vaccines for coronavirus. NHLBI-supported research aims to identify the causes of lasting heart and lung symptoms of COVID-19, find ways to prevent these problems, and improve treatment to promote rapid healing. A., & American Heart Association Pediatric Heart Failure and Transplantation Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young and Stroke Council (2021). It is estimated there are around 2 more cases per 100,000 second vaccine doses in people under 40 who received Moderna original formulation than Pfizer original formulation. Data sources: Klamer et al., 2022; Cordero et al., 2022; National Weather Service. Vaccination with BNT162b2 (Pfizer-BioNTech) or mRNA-1273 (Moderna). Myocarditis is an inflammation of the heart muscle; if it is accompanied by pericarditis, an inflammation of the thin tissue surrounding the heart (the pericardium), it is referred to as myopericarditis. The U.S. Food and Drug Administration on Friday added a warning to patient and provider fact sheets for the Pfizer and Moderna Covid-19 vaccines to indicate a rare risk of heart inflammation. 2022 Jun 1;5(6):e2218505. Patone, M., Mei, X. W., Handunnetthi, L., Dixon, S., Zaccardi, F., Shankar-Hari, M., Watkinson, P., Khunti, K., Harnden, A., Coupland, C., Channon, K. M., Mills, N. L., Sheikh, A., & Hippisley-Cox, J. Epidemiology of Myocarditis and Pericarditis Following mRNA Vaccination by Vaccine Product, Schedule, and Interdose Interval Among Adolescents and Adults in Ontario, Canada. I doubt we'll ever know. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Department of Health and Human Services. Its clear that vaccination can protect you from myocarditis by protecting you from COVID-19 infection. Jerome Fleg, M.D. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. The https:// ensures that you are connecting to the The risk of myocarditis linked with COVID-19 illness is several times greater than the risk from vaccination, and it is often more serious.3,5,8 This is because the SARS-CoV-2 virus invades cells of the heart, plus the body generates an overactive immune response to the infection. Use of trade names and commercial sources is for identification only and does not imply endorsement by the U.S. Department of
Among teenage boys, the rate of myocarditis or pericarditis after infection was at least 50 cases per 100,000 people, compared to at least 22 cases per 100,000 after the second vaccine dose.. Americans received more than 590 million doses of COVID-19 vaccines between December 2020 and June 2022.1 The most intensive safety monitoring system in U.S. history has made it possible to detect even very rare COVID-19 vaccine side effects, including myocarditis, which is inflammation of the heart muscle. Am J Cardiol 2021;149:95102. Both mRNA vaccines were authorized and recommended as a 2-dose schedule, with second doses administered 21 days (Pfizer-BioNTech) or 28 days (Moderna) after the first dose. Diagnostic evaluation might reveal an elevated troponin level or abnormal findings on electrocardiogram, echocardiogram, or cardiac magnetic resonance imaging (Table 1). Healthcare Providers: For additional recommendations and clinical guidance, visit Clinical Considerations: Myocarditis after mRNA COVID-19 Vaccines. Comparisons of the risk of myopericarditis between COVID-19 patients and individuals receiving COVID-19 vaccines: a population-based study. Pillay J, Gaudet L, Wingert A, Bialy L, Mackie AS, Paterson DI, Hartling L. BMJ. Viruses. Learn how NIH has improved basic understanding of the SARS-CoV-2 virus and sped up the development of COVID-19 vaccines, treatments, and testing. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Overall myocarditis rates among males in this age group were 2.97 per 100,000, which rose to 2.27 per 100,000 after the second dose. URL addresses listed in MMWR were current as of
The vaccine product-specific EUA fact sheet should be provided to all vaccine recipients and their caregivers before vaccination with any authorized COVID-19 vaccine. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Cookies used to make website functionality more relevant to you. They help us to know which pages are the most and least popular and see how visitors move around the site. <>/ExtGState<>/Pattern<>/Font<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 960 540] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>
More information is available, Travel requirements to enter the United States are changing, starting November 8, 2021. The crude reporting rates for cases of myocarditis within 7 days after COVID-19 vaccination exceeded the expected rates of myocarditis across multiple age and sex strata. Parents should speak with their childrens health care providers regarding the benefits and risks of vaccination against COVID-19. Acute clinical courses were generally mild; among 304 hospitalized patients with known clinical outcomes, 95% had been discharged at time of review, and none had died. the rates per million doses were roughly 52 with the Pfizer shots and . Conflict of Interest Disclosures: Dr Creech reported receiving grants from the National Institutes of Health for the Moderna and Janssen clinical trials and receiving personal fees from Astellas and Horizon. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. You will be subject to the destination website's privacy policy when you follow the link. Accessed June 29, 2022, from. Abara WE, Gee J, Marquez P, Woo J, Myers TR, DeSantis A, Baumblatt JAG, Woo EJ, Thompson D, Nair N, Su JR, Shimabukuro TT, Shay DK. doi: 10.1001/jamanetworkopen.2022.53845. These are normal signs that your body is making protective antibodies. endobj
FLEG: Myocarditis is an uncommon complication of SARS-CoV-2 infection. Treatment is often given in a hospital. Myocarditis usually goes away on its own with supportive care, including IV fluids, steroid therapy, and medicines to treat disorders of heart rhythm or pumping function. Am J Cardiovasc Pathol 1987; 1:314). During the COVID-19 pandemic, Fleg turned his attention to the effects of SARS-CoV-2 infection on the heart, including myocarditis. At the time of this report, 323 of these 484 cases were determined to meet criteria in CDCs case definitions for myocarditis, pericarditis, or myopericarditis by provider interview or medical record review (Table 1). National Library of Medicine The NHLBI supports and conducts research aimed at understanding risk factors for COVID-19, developing prevention and treatment strategies, and finding ways to hasten and enhance recovery. One thing we don't know is the real rate of myocarditis with the original two-dose primary series of Pfizer and Moderna. At that meeting, a chart showed that through early June, there was a higher rate of myocarditis among people who received Moderna than Pfizer-BioNTech about 20 per 1 million doses for. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Your chance of getting myocarditis after getting a COVID-19 vaccine is less than the chance of being struck by lightning during your lifetime. Patel, T., Kelleman, West, Z., M., Peter, A., Dove, M., Butto, A., & Oster, M. E. (2021). A small number of myocarditis and pericarditis cases have been reported for booster doses. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). myocarditis and pericarditis and the mRNA COVID-19 vaccines, made by Moderna and Pfizer-BioNTech, in some vaccine recipients. . These cookies may also be used for advertising purposes by these third parties.
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